肝硬化睡眠障礙的研究進(jìn)展

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Research Progress on Sleep Disorders in Cirrhosis

LIU Zhaoxia’ ，YANG Lei1 ，GUO Feng2

（1 The Fourth Clinical Medical Colege of Xinjiang Medical University，Urumqi 83oo99，China;2 Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital，Urumqi 83oo99，China）

AbstractSlepdisordersarecommon clinical manifestations intheprogresioofcirhosis，withaprevalenceofapproximately （204號(hào) 42% to 65% .Thesedisorders present in various forms，including insomnia，daytime sleepiness，andsleep-wake cycle inversion.Cirrosisndsleepdisordersexhbitadirectioalelatioship.Ononehand，theseverityfihosisisposivelyoelatd withthe prevalenceofsleepdisorders；ontheotherhand，poorsleepqualityexacerbates liver inflammation，promotestheprogressionoffbrosis，ndeasstssoietypriondfriluatelypctigptintalitflied sis.Thisviciouscycleunderscores theneedforgreatercinicalatention.Thisreviewsummarizestherecentadvances inthepatho genesisndspecificmanifestationsofsleepdisordersinihosisofdifrentetologies，mingtohancecliniciansawres， improve prognosis，and elevate the quality of life forpatientswith cirrhosis.

Keywords Cirrhosis；Sleep disorders；Pathogenesis；Assessment tools中圖分類號(hào)： R657.3+1 ;R338. 63 文獻(xiàn)標(biāo)識(shí)碼：A doi：10.3969/j. issn.2095-7130.2025.02.062

肝硬化是肝病的終末期階段，由于各種慢性肝病遷延不愈，患者肝功能損傷嚴(yán)重，肝臟生理結(jié)構(gòu)改變，不良事件發(fā)生概率增加，生命質(zhì)量受到顯著影響。（剩余8810字）