觀察參附注射液對(duì)急性心力衰竭患者 睡眠質(zhì)量的療效

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關(guān)鍵詞急性心力衰竭;參附注射液;中西醫(yī)結(jié)合;療效;炎癥介質(zhì);生命質(zhì)量;睡眠質(zhì)量;心血管疾病
Observation of the Therapeutic Effects of Shenfu Injection on Sleep Quality in Patients with Acute H
DINGHaiba
(Nanjing Hospital of Traditional Chinese Medicine,Nanjing 21oo22,China)
AbstractObjective:ToexploretheefectsofcombinedtreatmentofShenfu injectionand westernmedicineonpatients withacuteheartfailure,andtoobserve itsefectsonpatients’slepquality.Methods:Atotalof2OOpatientswithacuteheartflureadmitedto theEmergencyDepartmentofNanjing HospitalofTraditional Chinese Medicinefrom January219 toJanuary2024 were selected asthe studysubjects.They wererandomlydividedintoacontrol groupandanobservationgroupusingarandom number table metod,with10Opatientsineachgroup.Thecontrolgroupreceivedbasictreatment intervention;Theoservationgroupreceived Shenfu injectiononthebasis ofthecontrol group.The Pitsburgh SleepQuality Index(PSQI)wasused tocompare the changes in sleepqualitybetween two groups beforeandafterintervention.The Minnesota HeartFailure QualityofLife Scale(MLHFQ)wasusedtoevaluate thelifequalityof thetwo groups beforeandafterintervention.The myocardial injurymarkers(ncluding N-terminal probrainnatriureticpeptide levels,creatinekinase,creatine kinaseisoenzmelevels)and inflammatoryfactors (including high-sensitivityC-reactiveproteinandtumornecrosisfactoralpha)ofthetwogroupswereobserved.ResultsAfter treatment,the MLHFQscoresoftheobservationgroupweresignificantlylowerthanthoseof hecontrolgroup,andthePSQIscores of theobservationgroupweresignificantlylowerthanthoseofthecontrolgroup.Aftertreatment,thelevelsofN-terminalprobrain natriuretic peptide,creatine kinase,creatine kinase isoenzyme,high-sensitivity C-reactive protein,andtumor necrosis factor α in bothgroups decreased,andtheobservationgroupwassignificantlylowerthanthecontrol group.Thediferencesbetweehetwo groups were statistically significant( P<0.05 ). Conclusion:The combination of Shenfu injection and western medicine treatment caneffectivelyreducethelevelsofcardiacfunctionrelatedindicatorsand inflammatoryfactors inpatientswithacutehartfailure. It can also improve the daily life quality and sleep status of patients.
KeywordsAcute heartfailure;Shenfu injection;Combinationof traditional Chinesemedicineand western medicine;Therapeutic effect;Inflammatory factors;Life quality; Sleep quality;Cardiovascular disease
中圖分類號(hào): R541.6+1 ;R338. 63 文獻(xiàn)標(biāo)識(shí)碼:A doi:10.3969/j. issn.2095 -7130.2025.02.004
心力衰竭是一種嚴(yán)重的心血管疾病,其表現(xiàn)為不同程度的呼吸困難、肢體水腫、全身乏力以及日?;顒?dòng)能力受限。(剩余5341字)