肥胖型阻塞性睡眼呼吸暫停患者的睡眠監(jiān)測(cè)特點(diǎn)分析

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Analysis of Sleep Monitoring Characteristics in Obese Obstructive Sleep Apnea Patients

ANG Liu，LUO Xiaohua， WANG Haifeng，CHEN Huajiao， WANG Tingting，PENG Huanhuan， XIONG Qiong （Fuling Hospital Affiliated to Chongqing University， Chongqing 4O8ooo，China）

AbstractObjective：Tocomparetheclinicaldataand major sleep monitoring indexes ofobese andnon-obeseobstructive sleep apnea（OSA）patients，andtofurther explore thecharacteristicsofobeseOSApatients.Methods：Atotalof235patientswhocompleted polysomnographyexaminationattheSleepCentreofteDepartmentoftorhinolarygology，HeadandNckSugery，uling HospitalandclearlydiagnosedwithOSA wereselectedasthestudysubjects.Theclinical informationof hepatients，includingthe general informationand majorslepparameters werecolected.OSApatients were divided intonon-obese groupandobesegroup according tobodymassindex（BMI）.Thediferences inclinical informationandmajorsleepdetectionparametersbetweenthe two groups werecompared，andthecorelationbetweenBMandmajorsleepparameters wasanalysedResults：1）Te minmublood oxygen（ LSaO2 ） and mean blood oxygen（ MSaO2 ） of OSA patients in the obese group were significantly lower than those in the non-obese group（ P<0.05 ），and the apnea hypoventilation index（AHI） of OSA patients in the obese group was significantly higher than that of the non-obese group（ P<0.05）.2 The percentage of non-rapid eye movement（REM） sleep stage I（N1） in OSA patients in the obese group was significantly higher than that in the non-obese group（ P<0.05 ），and the percentage of nonrapid eye movement（N3）sleep stageI（N3）inOSA patients intheobese group wassignificantlylowerthanthat inthe non-obese group（ P<0.05 ）. 3）Spearman correlation analysis showed that BMI was positively correlated with AHI（ r=0.5，P<0.05 ）and negatively correlated with LSaO2 and N3 stage occupancy（ r=-0.5，-0.2，P<0.05 ）. Conclusion：BMI of OSA patients was positivelycorelatedwithtedegreeofnocturnalhypoxiaandnegativelycorrelatedwiththepercentageofdeepslp，suggesting that obesity exacerbates the degree of nocturnal hypoxia and deep sleep deprivation in OSA patients.

KeywordsObesity；Obstructiveslepapnoea；Sleep fragmentation；Nocturnalhypoxia；Sleepdeprivation；Apnoeahypoventilation index；N1 stage sleep percentage； N3 stage sleep percentage;

中圖分類號(hào)：R338.63；R56 文獻(xiàn)標(biāo)識(shí)碼：A doi：10.3969/j. issn.2095-7130.2025.02.006

阻塞性睡眠呼吸暫停（Obstructive Sleep Apnea，OSA）是指睡眠狀態(tài)下上氣道反復(fù)塌陷阻塞所引發(fā)的呼吸暫停及低通氣，導(dǎo)致患者睡眠結(jié)構(gòu)紊亂、血氧水平頻繁下降，可增加高血壓、心腦血管疾病、2型糖尿病、代謝綜合征的發(fā)病風(fēng)險(xiǎn)，甚至發(fā)生夜間猝死，嚴(yán)重影響生命質(zhì)量及危害公眾健康[1]。（剩余7802字）