右美托咪定輔助鎮(zhèn)靜對全身麻醉患者麻醉效果及術(shù)后睡眠質(zhì)量的影響

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Effectsof Dexmedetomidine-assisted Sedation on Anesthesia and Postoperative Sleep Quality in General Anesthesia Patients

WANG Xiufang，ZHENG Zhenzhen （Ji'nan Third People's Hospital，Ji'nan，China）

AbstractObjective：Toanalyzetheefectsofdexmedetomidine-asistedsedation inpatientsundergoing generalanesthesia. Methods：Atotalof8Ogeneralanesthesiapatients treatedatJi'nanThirdPeople'sHospital fromOctober2O22toOctober2023 were enrolled in the study and randomly divided into a control group（ n=40 ）and an observation group（ n=40 ）. The control groupreceived propofolanesthesia，whiletheobservationgroupreceiveddexmedetomidine-asistedsedationinaditiontothecontrol group'sprotocol.Anestheticeficacyandslepqualitywerecomparedbetweenthe twogroups.Results：Onpostoperativedays 1，3，and7，theAthensInsomnia Scale（AIS）scoresoftheobservationgroupweresignificantlylowerthanthoseofthecontrol group（ P<0.05） .At 15 minutes and 3O minutes post-extubation，Ramsay sedation scores difered significantly between the two groups （ P<0.05 ）. On the day of surgery，postoperative day 7，and the day before discharge，the Pitsburgh Sleep Quality Index （PSQI） scores of the observation group were significantly lower than those of the control group（ P<0.05 ） . Conclusion：Dexmedetomidie-asistedsedationdemonstratesideal efects ingeneralanesthesiaandsignificantlyimprovespatients’sleepquality， making it a valuable addition to clinical practice.

KeywordsGeneralanesthesia;Dexmedetomidine; Sedation；Anesthetic eficacy； Sleepquality；Adversereactions；Recovery time; Insomnia

中圖分類號：R338.63 文獻標(biāo)識碼：A doi：10.3969/j.issn.2095-7130.2025.02.019

全身麻醉是目前臨床應(yīng)用頻率極高的一種麻醉方式，通常采用肌注、靜脈注射、呼吸等方法使用麻醉藥物，以達到暫時抑制機體中樞神經(jīng)系統(tǒng)的效果，對于減輕術(shù)中疼痛，降低手術(shù)應(yīng)激以及保障手術(shù)的安全、順利進行具有重要作用[12]。（剩余4711字）