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右美托咪定輔助鎮(zhèn)靜對全身麻醉患者麻醉效果及術(shù)后睡眠質(zhì)量的影響

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Effectsof Dexmedetomidine-assisted Sedation on Anesthesia and Postoperative Sleep Quality in General Anesthesia Patients

WANG Xiufang,ZHENG Zhenzhen (Ji'nan Third People's Hospital,Ji'nan,China)

AbstractObjective:Toanalyzetheefectsofdexmedetomidine-asistedsedation inpatientsundergoing generalanesthesia. Methods:Atotalof8Ogeneralanesthesiapatients treatedatJi'nanThirdPeople'sHospital fromOctober2O22toOctober2023 were enrolled in the study and randomly divided into a control group( n=40 )and an observation group( n=40 ). The control groupreceived propofolanesthesia,whiletheobservationgroupreceiveddexmedetomidine-asistedsedationinaditiontothecontrol group'sprotocol.Anestheticeficacyandslepqualitywerecomparedbetweenthe twogroups.Results:Onpostoperativedays 1,3,and7,theAthensInsomnia Scale(AIS)scoresoftheobservationgroupweresignificantlylowerthanthoseofthecontrol group( P<0.05) .At 15 minutes and 3O minutes post-extubation,Ramsay sedation scores difered significantly between the two groups ( P<0.05 ). On the day of surgery,postoperative day 7,and the day before discharge,the Pitsburgh Sleep Quality Index (PSQI) scores of the observation group were significantly lower than those of the control group( P<0.05 ) . Conclusion:Dexmedetomidie-asistedsedationdemonstratesideal efects ingeneralanesthesiaandsignificantlyimprovespatients’sleepquality, making it a valuable addition to clinical practice.

KeywordsGeneralanesthesia;Dexmedetomidine; Sedation;Anesthetic eficacy; Sleepquality;Adversereactions;Recovery time; Insomnia

中圖分類號:R338.63 文獻標(biāo)識碼:A doi:10.3969/j.issn.2095-7130.2025.02.019

全身麻醉是目前臨床應(yīng)用頻率極高的一種麻醉方式,通常采用肌注、靜脈注射、呼吸等方法使用麻醉藥物,以達到暫時抑制機體中樞神經(jīng)系統(tǒng)的效果,對于減輕術(shù)中疼痛,降低手術(shù)應(yīng)激以及保障手術(shù)的安全、順利進行具有重要作用[12]。(剩余4711字)

目錄
monitor