孕早期空腹血糖、TG、血清鐵蛋白與妊娠期糖尿病風險的相關性

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[關鍵詞] 糖尿病，妊娠；妊娠初期；血糖；甘油三酯類；鐵蛋白質(zhì)類；預測[中圖分類號]R714.256;R446.112[文獻標志碼]A[文章編號]2096-5532（2025）03-0445-04doi：10.11712/jms.2096-5532.2025.61.102 [開放科學（資源服務）標識碼（OSID）]

[網(wǎng)絡出版]https：//link.cnki.net/urlid/37.1517.R.20250731.1031.001; 2025-07-3113：03：56

Associationoffastingbloodglucose，triglyceride，andserumferitininearlypregnancywiththeriskof gestationaldiabetesmelitus FAN Rui，GAO Shanshan，ZHANG Ke（Obstetrics Departmentof the Second Afiliated Hospital of Zhengzhou University， Zhengzhou 450000，China）

[Abstract]ObjectiveToinvestigate theassociationoffastingblood glucose（FPG），triglyceride（TG），andserumferritin （SF）inearlypregnancywithgestationaldiabetes melitus（GDM），andtoprovideabasisfortheearlyidentifcationanditerventionof GDM.MethodsAtotalof167 pregnant women whoatended DepartmentofObstetricsinourhospital from November 2021to December2023 wereenrolled，andacordingtotheresultsoforal glucosetolerance test，theyweredividedintoGDMgroup with76 patients andcontrol groupwith91patients.FPG，TG，and SFwerecomparedbetween thetwogroups，andtheir value in predictingGDMwasasessed.ResultsThere weresignificant diferencesbetweentheGDMgroupandthecontrol group nage， times of pregnancy，parity，familyhistoryof diabetes，bodymass index （BMI），F(xiàn)PG，TG，andSFinearly pregnancy（ χ2= 5.374-6.179，t=2.470-13.676，P<0.05） . The multivariate logistic regression analysis showed that BMI，F(xiàn)PG，TG，and SF in early pregnancy were independent risk factors for GDM（ P<0.05 ）.FPG，TG，and SF had an area under the ROC curve of 0.910， 0.678，andO.715，respectively，inpredictingGDM.ConclusionThelevelsofFPG，TG，andSFinearlypregnancyareassociated with the onset of GDM and have a certain value in predicting GDM.

[Key words]diabetes，gestational；pregnancytrimester，first；blood glucose；triglycerides；feritin；forecasting

全球約有 5%～6% 的孕婦罹患妊娠期糖尿病（GDM），且患病率持續(xù)攀升[1-2]。（剩余7090字）