避實擊虛法論治原發(fā)性干燥綜合征合并肺間質性病變

【中圖分類號】R249.2/.7 【文獻標志碼】A 【文章編號】1007-8517（2025）14-0091-05

DOI： 10.3969/j .issn.1007-8517.2025.14. zgmzmjyyzz202514018

TheStrategy of Addressing the UnderlyingDeficiencies While avoiding Exacerbation in the Treatment of Primary Sjogren's Syndrome Complicated by Interstitial Lung Disease

CHENG Xin1SONG Jiajia1CHEN Xing1PENG Jiehao1HUANG Yingling1WANGWeitao1 PENG Tao 1，2 “ 1.Shanxi University of Traditional Chinese Medicine，Taiyuan O3OO24，China; 2.Affiliated Integrated Traditional ChineseandWestern Medicine Hospital of Shanxi Universityof Traditional Chinese Medicine，Taiyuan O30013，China

Abstract：PrimarySjogren’ssyndromeisachronicinflammatoryautoimmunedisease，with interstitiallungdiseasebeing oneof its mostcommonseverecomplications，boastingahighincidenceandortalityrate.Curently，WesternmedicieoferslimitedthrapeuticeffcacyandomeswithsubstantialideefectsforthisconditionProfesorPengdiscoveredthatthisdiseaseisoftencaracter izedbyQi-Yindeficiencyasitscore，whichpersiststhroughoutthecourseofthedisease.WhenQi-Yinisdeficient，thechanels andcollteralsbcomeobstructed，leadingtotheaumulationofplegmandblodstasisovertime.Theavoiding themanifestations andatackingtherooapproachavoidsthemanifestationsofphlegmandbloodstasisndtargetstherootofQi-YindeficiencyThe maintreatmentprincipleis tosupplementQi-Yin，withoutfocusingondryingphlegmoreliminatingbloodstasis.Byrestoringphysi logical functionsandresistingtheprogresionofthedisease，thepatient’sconditioncanbeimprovedand progosisimproved.

Key words：Sjogren Syndrome；Interstitial Lung Disease；Clinical Approach；Medical Cases

原發(fā)性干燥綜合征（primary sjogren syndrome，pSS）是一種常見的以外分泌腺淋巴細胞浸潤為特征的慢性炎癥性自身免疫性疾病，總體患病率為0.3%～1% ，臨床表現(xiàn)多以口眼干燥、腮腺腫脹為主，往往伴有多器官、多系統(tǒng)損傷，呼吸系統(tǒng)是pSS常受累的系統(tǒng)之一，主要表現(xiàn)為肺間質病變（interstitial lungdisease，ILD），約有 22% 的pSS患者會繼發(fā) ILD[1] 。（剩余6775字）