國內(nèi)獻血者歸隊的現(xiàn)狀與思考
[摘要] 受試驗方法學(xué)、試劑、標(biāo)本狀態(tài)和獻血者個體因素等影響,部分獻血者因血液篩查單試劑反應(yīng)性被永久屏蔽,因未做進一步的確證試驗可能為假反應(yīng)性,對此國內(nèi)很多采供血機構(gòu)在進行獻血者的歸隊工作。本文就獻血者歸隊的定義、歸隊指南的版本更新、國內(nèi)采供血機構(gòu)進行歸隊工作情況作一綜述。
[關(guān)鍵詞] 無償獻血;假反應(yīng)性;獻血者歸隊
[中圖分類號] R457
[文獻標(biāo)志碼] A
[文章編號] 2096-5532(2024)04-0630-03doi:10.11712/jms.2096-5532.2024.60.126
[開放科學(xué)(資源服務(wù))標(biāo)識碼(OSID)]
[網(wǎng)絡(luò)出版] https://link.cnki.net/urlid/37.1517.R.20240919.1020.004;2024-09-20 08:23:39
Current status and reflection of the reentry of blood donors in China
FENG Qiuxia, HOU Yun, PAN Haiping, YANG Zhongsi(Qingdao Blood Center, Qingdao 266071, China); [Abstract]Due to the influence of test methodology, reagents, specimen status, and individual factors of blood donors, some blood donors have been permanently shielded due to single-reagent reactivity in blood screening, which might be false reactivity due to the lack of further confirmatory tests, and in this regard, blood collection and supply institutions in China are carrying out the reentry of blood donors. This article reviews the definition of blood donor reentry, version updates of reentry guidelines, and the reentry work of blood collection and supply institutions in China.
[Key words]voluntary blood donation; false reactive; blood donor reentry
隨著酶聯(lián)免疫吸附試驗(ELISA)方法和核酸檢測技術(shù)(NAT)的發(fā)展,試劑靈敏度不斷提高,在降低血液輸血風(fēng)險的同時不可避免導(dǎo)致檢測結(jié)果假反應(yīng)性增多[1-6],如梅毒螺旋體(TP)篩查反應(yīng)性標(biāo)本經(jīng)確證后,陽性率僅約0. 28%[7]。(剩余7738字)